Bridging Clinical Investigators and Statisticians
نویسندگان
چکیده
منابع مشابه
Bridging clinical investigators and statisticians: writing the statistical methodology for a research proposal.
Clinical investigators often find the thought of writing the statistical analysis plan daunting. Early collaboration between the clinical investigator and statistician can improve the study design and validity of the results by developing the statistical methodology that specifically addresses the research hypothesis. With the clinical investigator, a statistician often writes the statistical m...
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Design, execution and analysis of clinical studies involves several stakeholders with different professional backgrounds. Typically, principle investigators are familiar with standard office tools, data managers apply electronic data capture (EDC) systems and statisticians work with statistics software. Case report forms (CRFs) specify the data model of study subjects, evolve over time and cons...
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Clinical practice is changing rapidly. New cardiovascular drugs, antiinflammatory drugs, cancer chemotherapy, and other pharmacologic weapons are being added to physicians' therapeutic armamentarium virtually daily. Most clinical studies that bring new drugs from bench to bedside are financed by pharmaceutical companies. Many of these drug trials are rigorously designed, employing the skills of...
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ژورنال
عنوان ژورنال: Journal of Investigative Medicine
سال: 2009
ISSN: 1081-5589,1708-8267
DOI: 10.2310/jim.0b013e3181c2996c